Due to the challenges of habit, abuse, and misuse with opioids, even at advisable doses, reserve Promethazine HCl and Codeine Phosphate Oral Resolution for use in Grownup clients for whom the key benefits of cough suppression are envisioned to outweigh the threats, As well as in whom an suitable evaluation in the etiology of your cough has been built.

Will not make use of a household teaspoon to measure your medication. You could possibly accidentally take far too much. It is possible to question your pharmacist to the measuring unit it is best to use and how to measure the proper dose.

are pregnant or prepare to be pregnant. Promethazine Hydrochloride and Codeine Phosphate Oral Option can harm your unborn child. See “What's An important data I must know about Promethazine Hydrochloride and Codeine Phosphate Oral Answer?” are breastfeeding or plan to breastfeed. Codeine passes into your breast milk and could cause really serious Negative effects with your child such as amplified sleepiness, respiratory challenges (respiratory despair), and Dying. It's not acknowledged if promethazine can move into your breast milk.

DailyMed will deliver notification of updates and additions to Drug Label info at this time proven on This website via its RSS feed.

Stimulation can be evident, particularly in children and geriatric sufferers. Convulsions may perhaps seldom come about. A paradoxical-type reaction has become claimed in children receiving single doses of 75 mg to 125 mg orally, characterized by hyperexcitability and nightmares.

Considering the fact that recurrences of NMS are actually described with phenothiazines, the reintroduction of promethazine HCl must be very carefully considered.

Sedation This item relieves apprehension and induces a silent snooze from which the affected person can be very easily aroused.

Promethazine HCl and Codeine Phosphate Oral Solution is indicated for your non permanent relief of coughs and higher respiratory signs related to allergy or maybe the common chilly in patients 18 years of age and older.

g., amiodarone, quinidine) may possibly bring about an increase in codeine plasma concentrations and also a decrease in active metabolite morphine plasma concentration which could end in an analgesic efficacy reduction or signs and symptoms of opioid withdrawal.

Abuse and addiction are separate and distinct from physical dependence and tolerance. Wellness care suppliers really should be knowledgeable that habit is probably not accompanied by concurrent tolerance more info and indicators of Actual physical dependence in all addicts. In addition, abuse of opioids can arise within the absence of genuine dependancy.

The combination of promethazine hydrochloride and codeine phosphate is contraindicated in pediatric clients less than six a long time of age, mainly because the combination may well induce deadly respiratory depression in this age population. It is important that promethazine hydrochloride and codeine phosphate syrup is measured having an exact measuring product (see Safety measures-Details for Sufferers).

The opioid antagonists, naloxone and nalmefene, are certain antidotes for respiratory depression ensuing from opioid overdose. For clinically important respiratory or circulatory depression secondary to codeine overdose, administer an opioid antagonist. An antagonist should not be administered during the absence of clinically major respiratory melancholy. As the period of opioid reversal is expected to get less than the length of action of codeine in Promethazine HCl and Codeine Phosphate Oral Remedy, meticulously check the client until finally spontaneous respiration is reliably reestablished.

Make use of other supportive measures (such as oxygen and vasopressors) within the administration of circulatory shock and pulmonary edema as indicated. Cardiac arrest or arrhythmias will require Highly developed life-support techniques. Gastric emptying may very well be practical in taking away unabsorbed drug.

The diagnostic analysis of individuals using this type of syndrome is difficult. In arriving at a diagnosis, it's important to detect scenarios where the clinical presentation involves each severe healthcare ailment (e.